( Depression, anxiety, stress )
Mood & Anxiety
Mental health research needs people who know these conditions from the inside. Choose this area if your mood has been shaping your life, whether or not you have a diagnosis.

What studies here look at
Some studies compare medicines for depression or anxiety, including people for whom the first treatments did not help enough. Others test talking therapies, apps or programs delivered by video, and some combine the two.
There is also research into how sleep, exercise and daylight affect mood, and studies that use brain scans or blood tests to understand why one person responds to a treatment and another does not.
Who studies often ask for
Every study writes its own requirements, so read this as a picture of who tends to be asked, not a checklist.
- Adults living with depression, with or without treatment
- People with generalized anxiety, panic attacks or social anxiety
- People who have tried two or more treatments without enough relief
- People living with post-traumatic stress
( Taking part )
What a study might ask of you
Conversations
Structured interviews with a trained clinician about how you have been feeling.
Short questionnaires
Mood ratings every week or two, in person or online.
Therapy sessions
In therapy studies, regular sessions by video or at the site.
Safety calls
Check-ins between visits, and a number to call at any hour.
Questions worth asking
Take these to your first call with a research team, along with the questions in our guide to screening.
- What support is there if I feel worse during the study?
- Will I need to stop or change my current medicine?
- Are therapy sessions in person, by video, or my choice?
Hear about studies in this area
Join with Mood & Anxiety as your area and your ZIP code, and we will text you when a study near you fits.
Join for this areaSee what is recruiting today
ClinicalTrials.gov is the public U.S. registry of studies. This search lists recruiting studies for depression.
Open the registry search