( Mostly healthy adults )

Vaccine Studies

Vaccines are tested in people who are well, which makes this the area for anyone who wants to help research without having a particular condition.

A health worker placing a small bandage on a person’s upper arm

What studies here look at

Vaccine studies check how well a vaccine prompts the immune system and how people feel in the days after it. Early studies are small; later ones compare a new vaccine with an existing one across many sites.

Some studies follow participants through a whole flu or RSV season to see who becomes ill. Others test a vaccine in a group that needs extra protection, such as older adults or people with a long-term condition.

Who studies often ask for

Every study writes its own requirements, so read this as a picture of who tends to be asked, not a checklist.

  • Healthy adults of any age, from their late teens upward
  • Adults over 60, who are often needed for flu, RSV and shingles studies
  • People with a stable long-term condition such as diabetes
  • Pregnant people, for a small number of carefully designed studies

( Taking part )

What a study might ask of you

One or two shots

The vaccine or a comparison, given at the start of the study.

A reaction diary

Noting any soreness, fever or tiredness for about a week.

Blood samples

Taken before and after to measure the immune response.

Season check-ins

Calls or messages asking whether you have been unwell.

Questions worth asking

Take these to your first call with a research team, along with the questions in our guide to screening.

  • Could I receive a placebo instead of the vaccine?
  • Can I still get my regular flu shot while I am in the study?
  • Who do I contact if I feel unwell after the shot?

Hear about studies in this area

Join with Vaccine Studies as your area and your ZIP code, and we will text you when a study near you fits.

Join for this area

See what is recruiting today

ClinicalTrials.gov is the public U.S. registry of studies. This search lists recruiting studies for vaccines.

Open the registry search